Chemistry and related sciences





Hemolysin of Blewitt Mushroom?

The mushroom, Lepista nuda, Blewitt, is said to
contain a hemolysin toxin that is destroyed by cooking.
I have been unable to find any info on the name of
the toxin, the LD50, it’sextraction, etc.
Any help would be appreciated

What journal or book might have this info?

Thanks!
BGL

posted by admin in Uncategorized and have Comments (3)






3 Responses to “Hemolysin of Blewitt Mushroom?”

  1. admin says:

    "please respond in group" <big_george_l…@yahoo.com>

    | The mushroom, Lepista nuda, Blewitt, is said to
    | contain a hemolysin toxin that is destroyed by cooking.
    | I have been unable to find any info on the name of
    | the toxin, the LD50, it’sextraction, etc.
    | Any help would be appreciated
    |
    | What journal or book might have this info?
    |
    | Thanks!
    | BGL

    ————
    Denis R Benjamin
    Mushrooms : poisons and panaceas
    WH Freeman 1995

    Makes brief mention –

    Hydrocyanic acid

    Various cyanogens are common throughout the plant and fungal kingdoms. In mushrooms,
    hydrocyanic acid if found in a variety of genera, but because it so volatile and usually present
    in minute concentrations, it never poses much of health hazard. However, it is responsible for
    the delightful oil of almond odor in mushrooms such as Marasmius oreades (fairy ring mushroom).
    It is also present in other edible mushrooms such as the blewitt (Lepista nuda), …….. &c.

    By da – the ability to smell/taste HCN in genetic, some can’t.


    donald j haarmann
    ——————————­—
    If all the young ladies who attended the
    Yale promenade dance were laid end to
    end, no one would be the least surprised.
                                       Dorothy Parker

  2. admin says:

    donald haarmann wrote:
    > Denis R Benjamin
    > Mushrooms : poisons and panaceas
    > WH Freeman 1995

    > Hydrocyanic acid

    I found that references earlier, myself.  I believe the info isn’t
    the answer.  Paul Stamets of Fungi Perfecti co-authored a
    mushroom cultivation book that has a section on Lepista nuda,
    the Blewitt.  He states it is a hemolysin.  Unfortunately,
    the folks at F.P. didn’t know where he got his info when I queried
    them a few months ago.

    I am hoping someone knows of a rare reference or something else.

    Several species of fungi have been found to possess insecticidal
    properties, including this one.  But the name of toxin is NOT given.

    I am especially interested if the toxin exists in the mycelium mass
    itself or only in the fruitbodies.  And how soluble it is and with
    what.
    And any other details available.

    Please……….

    Thanks!

    BGL

  3. admin says:

    On Mon, 9 Oct 2006, please respond in group wrote:

    > I found that references earlier, myself.  I believe the info isn’t the
    > answer.  Paul Stamets of Fungi Perfecti co-authored a mushroom
    > cultivation book that has a section on Lepista nuda, the Blewitt.  He
    > states it is a hemolysin. Unfortunately, the folks at F.P. didn’t know
    > where he got his info when I queried them a few months ago.

    Have you written to Mr Stamets himself? If he’s going to run around making
    wild allegations like that, he really ought to be able to produce some
    evidence for them.

    > I am especially interested if the toxin exists in the mycelium mass
    > itself or only in the fruitbodies.  And how soluble it is and with what.

    As i understand it, haemolysins are proteins; as such, they’ll be soluble
    in solutions that are, roughly, water. A bit of buffering around pH 7,
    some salt, and some nonionic detergent probably wouldn’t hurt.

    The assay for haemolysin is fairly straightforard – culture your organism,
    or spot some extract, on a blood agar plate, and look for lysis of the red
    cells. You should be able to use this to work out if this alleged
    haemolysin is present, and if it is, as an assay to guide refinement of an
    extraction and purification strategy.

    tom


    Taking care of business







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