I use Sephadex SP-C25 and Dowex 50×2 cation exchange resins to clean up
reaction mixtures during syntheses of Co(III) complexes – trouble is, there
always seems to be something that binds irreversibly to the column and I end
up with a load of dirty resin that even 0.2M HCl (sephadex) or 6M HCl (
dowex) won’t shift. Does anyone in netland have any hints on how to clean
these resins up? Has anyone tried elution with mild reducing agents? The
resins are so expensive they can’t just be chucked. Any tips would be
appreciated.

Thanks…

Allan
*****************************************************************************
Allan Blackman                                    black…@alkali.otago.ac.nz
Department of Chemistry
University of Otago
Dunedin
NEW ZEALAND
*****************************************************************************